DIPG-34. PRECLINICAL PRECISION TESTING OF PNOC003 BIOPSY DERIVED MODELS OF DIPG

RATIONALE: One of the major hurdles in developing effective treatment for children with DIPG includes the lack of extensive combinatorial studies targeting major driver oncogenic pathways. Combination of H3K27M and TP53 mutations are found in over 50% of DIPG tumors, however, there is a lack of effe...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Panditharatna, Eshini, Yadavili, Sridevi, Yang, Xiaodong, Zhang, Jie, Truffaux, Nathalene, Zhai, Yuying, Kambhampati, Madhuri, Zhang, Bo, Zhu, Yuankun, Jain, Payal, Kline, Cassie, Packer, Roger J, Prados, Michael, Gupta, Nalin, Resnick, Adam, Mueller, Sabine, Nazarian, Javad
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Diffuse Intrinsic Pontine Glioma (DIPG)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477401/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.055
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