DIPG-34. PRECLINICAL PRECISION TESTING OF PNOC003 BIOPSY DERIVED MODELS OF DIPG

RATIONALE: One of the major hurdles in developing effective treatment for children with DIPG includes the lack of extensive combinatorial studies targeting major driver oncogenic pathways. Combination of H3K27M and TP53 mutations are found in over 50% of DIPG tumors, however, there is a lack of effe...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Neuro Oncol
Main Authors: Panditharatna, Eshini, Yadavili, Sridevi, Yang, Xiaodong, Zhang, Jie, Truffaux, Nathalene, Zhai, Yuying, Kambhampati, Madhuri, Zhang, Bo, Zhu, Yuankun, Jain, Payal, Kline, Cassie, Packer, Roger J, Prados, Michael, Gupta, Nalin, Resnick, Adam, Mueller, Sabine, Nazarian, Javad
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2019
נושאים:
Diffuse Intrinsic Pontine Glioma (DIPG)
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477401/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.055
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