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Targeting the α4-α5 dimerization interface of K-RAS inhibits tumor formation in vivo
RAS genes are the most commonly mutated oncogenes in human cancers. Despite tremendous efforts over the past several decades, however, RAS-specific inhibitors remain elusive. Thus, targeting RAS remains a highly sought after goal of cancer research. Previously, we reported a new approach to inhibit...
Kaydedildi:
| Yayımlandı: | Oncogene |
|---|---|
| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6474814/ https://ncbi.nlm.nih.gov/pubmed/30573767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0636-y |
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