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Structural Dynamics of the Activation of Elongation Factor 2 Kinase by Ca(2+)-Calmodulin
Eukaryotic elongation factor 2 kinase (eEF-2K), the only known calmodulin (CaM) activated α–kinase, phosphorylates eukaryotic elongation factor 2 (eEF-2) on a specific threonine (Thr-56) diminishing its affinity for the ribosome and reducing the rate of nascent chain elongation during translation. D...
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| Publicado no: | J Mol Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6474356/ https://ncbi.nlm.nih.gov/pubmed/29800565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.05.033 |
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