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Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin
Binding of Ca(2+)-loaded calmodulin (CaM) activates eukaryotic elongation factor 2 kinase (eEF-2K) that phosphorylates eEF-2, its only known cellular target, leading to a decrease in global protein synthesis. Here, using an eEF-2K-derived peptide (eEF-2K(CBD)) that encodes the region necessary for i...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014583/ https://ncbi.nlm.nih.gov/pubmed/27499441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.06.015 |
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