Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin

Binding of Ca(2+)-loaded calmodulin (CaM) activates eukaryotic elongation factor 2 kinase (eEF-2K) that phosphorylates eEF-2, its only known cellular target, leading to a decrease in global protein synthesis. Here, using an eEF-2K-derived peptide (eEF-2K(CBD)) that encodes the region necessary for i...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Structure
Asıl Yazarlar: Lee, Kwangwoon, Alphonse, Sébastien, Piserchio, Andrea, Tavares, Clint D. J., Giles, David H., Wellmann, Rebecca M., Dalby, Kevin N., Ghose, Ranajeet
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014583/
https://ncbi.nlm.nih.gov/pubmed/27499441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.06.015
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