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Structural dynamics of the complex of calmodulin with a minimal functional construct of eukaryotic elongation factor 2 kinase and the role of Thr348 autophosphorylation

The calmodulin (CaM) activated α‐kinase, eukaryotic elongation factor 2 kinase (eEF‐2K), plays a central role in regulating translational elongation by phosphorylating eukaryotic elongation factor 2 (eEF‐2), thereby reducing its ability to associate with the ribosome and suppressing global protein s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Protein Sci
Päätekijät: Piserchio, Andrea, Long, Kimberly, Lee, Kwangwoon, Kumar, Eric A., Abzalimov, Rinat, Dalby, Kevin N., Ghose, Ranajeet
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Inc. 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138526/
https://ncbi.nlm.nih.gov/pubmed/33890716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4087
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