Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes

SUMMARY: Non-retroviral integrated RNA viral sequences (NIRVs) potentially encoding ~280 amino acid homologs to filovirus VP35 proteins are present across the Myotis genus of bats. These are estimated to have been maintained for ~18 million years, indicating their co-option. To address the reasons f...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Edwards, Megan R., Liu, Hejun, Shabman, Reed S., Ginell, Garrett M., Luthra, Priya, Ramanan, Parmeshwaran, Keefe, Lisa J., Köllner, Bernd, Amarasinghe, Gaya K., Taylor, Derek J., Leung, Daisy W., Basler, Christopher F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474348/
https://ncbi.nlm.nih.gov/pubmed/30044983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.045
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk