Development of RNA aptamers targeting Ebola virus VP35

Viral protein 35 (VP35), encoded by filoviruses, are multifunctional dsRNA binding proteins that play important roles in viral replication, innate immune evasion and pathogenesis. The multifunctional nature of these proteins also presents opportunities to develop countermeasures that target distinct...

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Main Authors: Binning, Jennifer M., Wang, Tianjiao, Luthra, Priya, Shabman, Reed S., Borek, Dominika M., Liu, Gai, Xu, Wei, Leung, Daisy W., Basler, Christopher F., Amarasinghe, Gaya K.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909728/
https://ncbi.nlm.nih.gov/pubmed/24067086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400704d
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