Development of RNA aptamers targeting Ebola virus VP35

Viral protein 35 (VP35), encoded by filoviruses, are multifunctional dsRNA binding proteins that play important roles in viral replication, innate immune evasion and pathogenesis. The multifunctional nature of these proteins also presents opportunities to develop countermeasures that target distinct...

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Bibliografiske detaljer
Main Authors: Binning, Jennifer M., Wang, Tianjiao, Luthra, Priya, Shabman, Reed S., Borek, Dominika M., Liu, Gai, Xu, Wei, Leung, Daisy W., Basler, Christopher F., Amarasinghe, Gaya K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909728/
https://ncbi.nlm.nih.gov/pubmed/24067086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400704d
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