An intrinsically disordered peptide from Ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions

During viral RNA synthesis, Ebola virus (EBOV) nucleoprotein (NP) alternates between an RNA template-bound form and a template-free form to provide the viral polymerase access to the RNA template. In addition, newly synthesized NP must be prevented from indiscriminately binding to noncognate RNAs. H...

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Udgivet i:Cell Rep
Main Authors: Leung, Daisy W., Borek, Dominika M., Luthra, Priya, Binning, Jennifer M., Anantpadma, Manu, Liu, Gai, Harvey, Ian B., Su, Zhaoming, Endlich-Frazier, Ariel, Pan, Juanli, Shabman, Reed S., Chiu, Wah, Davey, Robert, Otwinowski, Zbyszek, Basler, Christopher F., Amarasinghe, Gaya K.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599368/
https://ncbi.nlm.nih.gov/pubmed/25865894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.034
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