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An intrinsically disordered peptide from Ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions
During viral RNA synthesis, Ebola virus (EBOV) nucleoprotein (NP) alternates between an RNA template-bound form and a template-free form to provide the viral polymerase access to the RNA template. In addition, newly synthesized NP must be prevented from indiscriminately binding to noncognate RNAs. H...
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Publicado no: | Cell Rep |
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Main Authors: | , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4599368/ https://ncbi.nlm.nih.gov/pubmed/25865894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.034 |
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