Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

The VP35 protein encoded by the highly pathogenic Ebola virus facilitates immune evasion by antagonizing antiviral signaling pathways, including those initiated by RIG-I like receptors. Here we report the crystal structure of Ebola VP35 interferon inhibitory domain (IID) bound to short double-strand...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Leung, Daisy W., Prins, Kathleen C., Borek, Dominika M., Farahbakhsh, Mina, Tufariello, JoAnn M., Ramanan, Parameshwaran, Nix, Jay C., Helgeson, Luke, Otwinowski, Zbyszek, Honzatko, Richard B., Basler, Christopher F., Amarasinghe, Gaya K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872155/
https://ncbi.nlm.nih.gov/pubmed/20081868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1765
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados