Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins

VP35 is one of seven structural proteins encoded by the Ebola viral genome and mediates viral replication, nucleocapsid formation and host immune suppression. The C-terminal interferon inhibitory domain (IID) of VP35 is critical for dsRNA binding and interferon inhibition. The wild-type VP35 IID str...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Leung, Daisy W., Borek, Dominika, Farahbakhsh, Mina, Ramanan, Parameshwaran, Nix, Jay C., Wang, Tianjiao, Prins, Kathleen C., Otwinowski, Zbyszek, Honzatko, Richard B., Helgeson, Luke A., Basler, Christopher F., Amarasinghe, Gaya K.
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2010
Sujets:
Crystallization Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882771/
https://ncbi.nlm.nih.gov/pubmed/20516601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110013266
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires