Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins

VP35 is one of seven structural proteins encoded by the Ebola viral genome and mediates viral replication, nucleocapsid formation and host immune suppression. The C-terminal interferon inhibitory domain (IID) of VP35 is critical for dsRNA binding and interferon inhibition. The wild-type VP35 IID str...

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書誌詳細
主要な著者: Leung, Daisy W., Borek, Dominika, Farahbakhsh, Mina, Ramanan, Parameshwaran, Nix, Jay C., Wang, Tianjiao, Prins, Kathleen C., Otwinowski, Zbyszek, Honzatko, Richard B., Helgeson, Luke A., Basler, Christopher F., Amarasinghe, Gaya K.
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2010
主題:
Crystallization Communications
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882771/
https://ncbi.nlm.nih.gov/pubmed/20516601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110013266
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