Crystallization and preliminary X-ray analysis of Ebola VP35 interferon inhibitory domain mutant proteins

VP35 is one of seven structural proteins encoded by the Ebola viral genome and mediates viral replication, nucleocapsid formation and host immune suppression. The C-terminal interferon inhibitory domain (IID) of VP35 is critical for dsRNA binding and interferon inhibition. The wild-type VP35 IID str...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Leung, Daisy W., Borek, Dominika, Farahbakhsh, Mina, Ramanan, Parameshwaran, Nix, Jay C., Wang, Tianjiao, Prins, Kathleen C., Otwinowski, Zbyszek, Honzatko, Richard B., Helgeson, Luke A., Basler, Christopher F., Amarasinghe, Gaya K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2010
Gaiak:
Crystallization Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882771/
https://ncbi.nlm.nih.gov/pubmed/20516601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110013266
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