Caricamento...

Specific spatial learning deficits become severe with age in β-amyloid precursor protein transgenic mice that harbor diffuse β-amyloid deposits but do not form plaques

Memory impairment progressing to dementia is the main clinical symptom of Alzheimer's disease (AD). AD is characterized histologically by the presence of β-amyloid (Aβ) plaques and neurofibrillary tangles in specific brain regions. Although Aβ derived from the Aβ precursor protein (β-APP) is be...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Koistinaho, Milla, Ort, Michael, Cimadevilla, Jose M., Vondrous, Roman, Cordell, Barbara, Koistinaho, Jari, Bures, Jan, Higgins, Linda S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC64740/
https://ncbi.nlm.nih.gov/pubmed/11724968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261562998
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !