載入...

Complement C3 Deficiency Leads to Accelerated Amyloid β Plaque Deposition and Neurodegeneration and Modulation of the Microglia/Macrophage Phenotype in Amyloid Precursor Protein Transgenic Mice

Complement factor C3 is the central component of the complement system and a key inflammatory protein activated in Alzheimer's disease (AD). Previous studies demonstrated that inhibition of C3 by overexpression of soluble complement receptor-related protein y in an AD mouse model led to reduced...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Maier, Marcel, Peng, Ying, Jiang, Liying, Seabrook, Timothy J., Carroll, Michael C., Lemere, Cynthia A.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329761/
https://ncbi.nlm.nih.gov/pubmed/18562603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0829-08.2008
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!