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Compound AD16 Reduces Amyloid Plaque Deposition and Modifies Microglia in a Transgenic Mouse Model of Alzheimer’s Disease

[Image: see text] Microglial dysfunction is involved in the pathological cascade of Alzheimer’s disease (AD). The regulation of microglial function may be a novel strategy for AD therapy. We previously reported the discovery of AD16, an antineuroinflammatory molecule that could improve learning and...

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Pubblicato in:ACS Pharmacol Transl Sci
Autori principali: Sun, Ping, Yue, Hu, Xing, Qi, Deng, Wenmin, Ou, Yitao, Pan, Guangjin, Zhong, Xiaofen, Hu, Wenhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2020
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7737203/
https://ncbi.nlm.nih.gov/pubmed/33344892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00073
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