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Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer’s disease

BACKGROUND: Microglia are known as resident immune cells in the brain. β-amyloid (Aβ) plaques in the brain of Alzheimer’s disease (AD) are surrounded by microglia, but whether and how microglia affect the formation and maintenance of plaques remains controversial. METHODS: We depleted microglia by i...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Zhao, Ruohe, Hu, Wanling, Tsai, Julia, Li, Wei, Gan, Wen-Biao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468952/
https://ncbi.nlm.nih.gov/pubmed/28606182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0188-6
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