IL-1β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia

BACKGROUND: Neuroinflammation is thought to contribute to the pathogenesis of Alzheimer’s disease (AD), yet numerous studies have demonstrated a beneficial role for neuroinflammation in amyloid plaque clearance. We have previously shown that sustained expression of IL-1β in the hippocampus of APP/PS...

Full description

Saved in:
Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Rivera-Escalera, Fátima, Pinney, Jonathan J., Owlett, Laura, Ahmed, Hoda, Thakar, Juilee, Olschowka, John A., Elliott, Michael R., O’Banion, M. Kerry
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902486/
https://ncbi.nlm.nih.gov/pubmed/31822279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1645-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items