Passive Amyloid Immunotherapy Clears Amyloid and Transiently Activates Microglia in a Transgenic Mouse Model of Amyloid Deposition

The role of microglia in the removal of amyloid deposits after systemically administered anti-Aβ antibodies remains unclear. In the current study, we injected Tg2576 APP transgenic mice weekly with an anti-Aβ antibody for 1, 2, or 3 months such that all mice were 22 months at the end of the study. I...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wilcock, Donna M., Rojiani, Amyn, Rosenthal, Arnon, Levkowitz, Gil, Subbarao, Sangeetha, Alamed, Jennifer, Wilson, David, Wilson, Nedda, Freeman, Melissa J., Gordon, Marcia N., Morgan, Dave
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729674/
https://ncbi.nlm.nih.gov/pubmed/15240806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1090-04.2004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados