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Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia
Amyloid β-peptide (Aβ), the pathogenic agent of Alzheimer disease, is a physiological metabolite whose levels are constantly controlled in normal brain. Recent studies have demonstrated that a fraction of extracellular Aβ is associated with exosomes, small membrane vesicles of endosomal origin, alth...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322859/ https://ncbi.nlm.nih.gov/pubmed/22303002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.324616 |
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