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TREM2 enables amyloid β clearance by microglia

In a recent paper published in Cell, Wang et al. report that deficiency of triggering receptor expressed on myeloid cells 2 (TREM2) augments amyloid β accumulation and neuronal loss in a mouse model of Alzheimer's disease. TREM2 acts as a signaling receptor involved in innate immunity for the n...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Res
Egile nagusia: Rivest, Serge
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423078/
https://ncbi.nlm.nih.gov/pubmed/25828532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.37
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