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TREM2 enables amyloid β clearance by microglia
In a recent paper published in Cell, Wang et al. report that deficiency of triggering receptor expressed on myeloid cells 2 (TREM2) augments amyloid β accumulation and neuronal loss in a mouse model of Alzheimer's disease. TREM2 acts as a signaling receptor involved in innate immunity for the n...
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| Udgivet i: | Cell Res |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423078/ https://ncbi.nlm.nih.gov/pubmed/25828532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.37 |
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