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Sphingolipid-modulated Exosome Secretion Promotes Clearance of Amyloid-β by Microglia

Amyloid β-peptide (Aβ), the pathogenic agent of Alzheimer disease, is a physiological metabolite whose levels are constantly controlled in normal brain. Recent studies have demonstrated that a fraction of extracellular Aβ is associated with exosomes, small membrane vesicles of endosomal origin, alth...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yuyama, Kohei, Sun, Hui, Mitsutake, Susumu, Igarashi, Yasuyuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322859/
https://ncbi.nlm.nih.gov/pubmed/22303002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.324616
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