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Exosomes as Carriers of Alzheimer's Amyloid-ß
The intracerebral level of the aggregation-prone peptide, amyloid-ß (Aß), is constantly maintained by multiple clearance mechanisms, including several degradation enzymes, and brain efflux. Disruption of the clearance machinery and the resultant Aß accumulation gives rise to neurotoxic assemblies, l...
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| Pubblicato in: | Front Neurosci |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5403946/ https://ncbi.nlm.nih.gov/pubmed/28487629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00229 |
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