Amyloid-Peptide Vaccinations Reduce β-Amyloid Plaques but Exacerbate Vascular Deposition and Inflammation in the Retina of Alzheimer’s Transgenic Mice

Alzheimer’s disease (AD) is pathologically characterized by accumulation of β-amyloid (Aβ) protein deposits and/or neurofibrillary tangles in association with progressive cognitive deficits. Although numerous studies have demonstrated a relationship between brain pathology and AD progression, the Al...

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Detalhes bibliográficos
Main Authors: Liu, Bingqian, Rasool, Suhail, Yang, Zhikuan, Glabe, Charles G., Schreiber, Steven S., Ge, Jian, Tan, Zhiqun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774073/
https://ncbi.nlm.nih.gov/pubmed/19834067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090159
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