Structural Basis of Polyketide Synthase O-Methylation

Modular type I polyketide synthases (PKSs) produce some of the most chemically complex metabolites in nature through a series of multi-enzyme modules. Each module contains a variety of catalytic domains to selectively tailor the growing molecule. PKS O-methyltransferases (O-MTs) are predicted to met...

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Bibliografske podrobnosti
izdano v:ACS Chem Biol
Main Authors: Skiba, Meredith A., Bivins, Marissa M., Schultz, John R., Bernard, Steffen M., Fiers, William D., Dan, Qingyun, Kulkarni, Sarang, Wipf, Peter, Gerwick, William H., Sherman, David H., Aldrich, Courtney C., Smitha, Janet L.
Format: Artigo
Jezik:Inglês
Izdano: 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470024/
https://ncbi.nlm.nih.gov/pubmed/30489068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00687
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