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Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis

Polyketide synthase (PKS) enzymes continue to hold great promise as synthetic biology platforms for the production of novel therapeutic agents, biofuels and commodity chemicals. Dehydratase (DH) catalytic domains play an important role during polyketide biosynthesis through the dehydration of the na...

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Publicat a:J Am Chem Soc
Autors principals: Fiers, William D., Dodge, Greg J., Sherman, David H., Smith, Janet L., Aldrich, Courtney C.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590676/
https://ncbi.nlm.nih.gov/pubmed/27960309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09748
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