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Vinylogous Dehydration by a Polyketide Dehydratase Domain in Curacin Biosynthesis

Polyketide synthase (PKS) enzymes continue to hold great promise as synthetic biology platforms for the production of novel therapeutic agents, biofuels and commodity chemicals. Dehydratase (DH) catalytic domains play an important role during polyketide biosynthesis through the dehydration of the na...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Fiers, William D., Dodge, Greg J., Sherman, David H., Smith, Janet L., Aldrich, Courtney C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590676/
https://ncbi.nlm.nih.gov/pubmed/27960309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09748
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