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The Structural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic Pathways
Sulfated molecules with diverse functions are common in biology, but sulfonation as a method to activate a metabolite for chemical catalysis is rare. Catalytic activity was characterized and crystal structures were determined for two such “activating” sulfotransferases (STs) that sulfonate β-hydroxy...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528841/ https://ncbi.nlm.nih.gov/pubmed/22991895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300385m |
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