Structural Basis of Polyketide Synthase O-Methylation

Modular type I polyketide synthases (PKSs) produce some of the most chemically complex metabolites in nature through a series of multi-enzyme modules. Each module contains a variety of catalytic domains to selectively tailor the growing molecule. PKS O-methyltransferases (O-MTs) are predicted to met...

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Publicat a:ACS Chem Biol
Autors principals: Skiba, Meredith A., Bivins, Marissa M., Schultz, John R., Bernard, Steffen M., Fiers, William D., Dan, Qingyun, Kulkarni, Sarang, Wipf, Peter, Gerwick, William H., Sherman, David H., Aldrich, Courtney C., Smitha, Janet L.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470024/
https://ncbi.nlm.nih.gov/pubmed/30489068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00687
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