Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

Aging is accompanied by progressive declines in skeletal muscle mass and strength and impaired regenerative capacity, predisposing older adults to debilitating age-related muscle deteriorations and severe morbidity. Muscle stem cells (muSCs) that proliferate, differentiate to fusion-competent myobla...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biochem Pharmacol
Päätekijät: Neelakantan, Harshini, Brightwell, Camille R., Graber, Ted G., Maroto, Rosario, Leo Wang, Hua-Yu, McHardy, Stanton F., Papaconstantinou, John, Fry, Christopher S., Watowich, Stanley J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469996/
https://ncbi.nlm.nih.gov/pubmed/30753815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2019.02.008
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia