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Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?

This review covers the current knowledge of the cytochrome P450 enzymes (CYPs) of the human pathogen Mycobacterium tuberculosis (Mtb) and their endogenous redox partners, focusing on their biological function, expression, regulation, involvement in antibiotic resistance, and suitability for exploita...

詳細記述

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書誌詳細
出版年:Appl Microbiol Biotechnol
主要な著者: Ortega Ugalde, Sandra, Boot, Maikel, Commandeur, Jan N. M., Jennings, Paul, Bitter, Wilbert, Vos, J. Chris
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469627/
https://ncbi.nlm.nih.gov/pubmed/30810776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-019-09697-z
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