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Evaluation of Luminogenic Substrates as Probe Substrates for Bacterial Cytochrome P450 Enzymes: Application to Mycobacterium tuberculosis

Several cytochrome P450 enzymes (CYPs) encoded in the genome of Mycobacterium tuberculosis (Mtb) are considered potential new drug targets due to the essential roles they play in bacterial viability and in the establishment of chronic intracellular infection. Identification of inhibitors of Mtb CYPs...

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Ortega Ugalde, Sandra, Ma, Dongping, Cali, James J., Commandeur, Jan N. M.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651611/
https://ncbi.nlm.nih.gov/pubmed/31208248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555219853220
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