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Reaction of Mycobacterium tuberculosis Cytochrome P450 Enzymes with Nitric Oxide†
During the initial growth infection stage of Mycobacterium tuberculosis (Mtb), (•)NO produced by host macrophages inhibits heme-containing terminal cytochrome oxidases, inactivates iron/sulfur proteins and promotes entry into latency. Here we evaluate the potential of (•)NO as an inhibitor of Mtb cy...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681326/ https://ncbi.nlm.nih.gov/pubmed/19146393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801595t |
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