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Nitric oxide dioxygenation reaction in DevS and the initial response to nitric oxide in Mycobacterium tuberculosis

DevS and DosT from Mycobacterium tuberculosis (MTB) are paralogous heme-based sensor kinases that respond to hypoxia and to low concentrations of nitric oxide (NO). Both proteins work with the response regulator DevR as a two-component regulatory system to induce the dormancy regulon in MTB. While D...

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Detalhes bibliográficos
Main Authors: Yukl, Erik T., Ioanoviciu, Alexandra, Sivaramakrishnan, Santhosh, Nakano, Michiko M., Ortiz de Montellano, Paul R., Moënne-Loccoz, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079480/
https://ncbi.nlm.nih.gov/pubmed/21250657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1015315
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