Caricamento...
Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury
[Image: see text] Acetaminophen misuse is a leading cause of acute liver failure and liver transplantation for which therapy is poorly effective. FXR ligands have shown effective in reducing liver injury in several experimental and clinical settings. In this Letter, we have elaborated on the structu...
Salvato in:
| Pubblicato in: | ACS Med Chem Lett |
|---|---|
| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2018
|
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6466548/ https://ncbi.nlm.nih.gov/pubmed/30996771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00423 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|