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Aggregation of Microtubule Binding Repeats of Tau Protein is Promoted by Cu(2+)

[Image: see text] Understanding the factors that give rise to tau aggregation and reactive oxygen species (ROS) is the key aspect in Alzheimer’s disease pathogenesis. Microtubule (MT) binding repeats of tau protein were suggested to play a critical role in tau aggregation. Here, we show that the int...

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Bibliographic Details
Published in:ACS Omega
Main Authors: Ahmadi, Soha, Zhu, Shaolong, Sharma, Renu, Wu, Bing, Soong, Ronald, Dutta Majumdar, R., Wilson, Derek J., Simpson, Andre J., Kraatz, Heinz-Bernhard
Format: Artigo
Language:Inglês
Published: American Chemical Society 2019
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463671/
https://ncbi.nlm.nih.gov/pubmed/31001602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03595
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