Repeat motifs of tau bind to the insides of microtubules in the absence of taxol

The tau family of microtubule-asssociated proteins has a microtubule-binding domain which includes three or four conserved sequence repeats. Pelleting assays show that when tubulin and tau are co- assembled into microtubules, the presence of taxol reduces the amount of tau incorporated. In the absen...

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Bibliographic Details
Main Authors: Kar, Santwana, Fan, Juan, Smith, Michael J., Goedert, Michel, Amos, Linda A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC140040/
https://ncbi.nlm.nih.gov/pubmed/12505985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg001
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