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Aggregation of Microtubule Binding Repeats of Tau Protein is Promoted by Cu(2+)

[Image: see text] Understanding the factors that give rise to tau aggregation and reactive oxygen species (ROS) is the key aspect in Alzheimer’s disease pathogenesis. Microtubule (MT) binding repeats of tau protein were suggested to play a critical role in tau aggregation. Here, we show that the int...

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Dettagli Bibliografici
Pubblicato in:ACS Omega
Autori principali: Ahmadi, Soha, Zhu, Shaolong, Sharma, Renu, Wu, Bing, Soong, Ronald, Dutta Majumdar, R., Wilson, Derek J., Simpson, Andre J., Kraatz, Heinz-Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2019
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463671/
https://ncbi.nlm.nih.gov/pubmed/31001602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03595
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