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Aggregation of Microtubule Binding Repeats of Tau Protein is Promoted by Cu(2+)

[Image: see text] Understanding the factors that give rise to tau aggregation and reactive oxygen species (ROS) is the key aspect in Alzheimer’s disease pathogenesis. Microtubule (MT) binding repeats of tau protein were suggested to play a critical role in tau aggregation. Here, we show that the int...

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Библиографические подробности
Опубликовано в: :ACS Omega
Главные авторы: Ahmadi, Soha, Zhu, Shaolong, Sharma, Renu, Wu, Bing, Soong, Ronald, Dutta Majumdar, R., Wilson, Derek J., Simpson, Andre J., Kraatz, Heinz-Bernhard
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2019
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463671/
https://ncbi.nlm.nih.gov/pubmed/31001602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03595
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