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Oligomer Diversity during the Aggregation of the Repeat Region of Tau

[Image: see text] The molecular mechanism of protein aggregation is of both fundamental and clinical importance as amyloid aggregates are linked to a number of neurodegenerative disorders. Such protein aggregates include macroscopic insoluble fibrils as well as small soluble oligomeric species. Time...

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Publicado en:ACS Chem Neurosci
Autores principales: Kjaergaard, Magnus, Dear, Alexander J., Kundel, Franziska, Qamar, Seema, Meisl, Georg, Knowles, Tuomas P. J., Klenerman, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2018
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302314/
https://ncbi.nlm.nih.gov/pubmed/29953200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00250
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