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Integrated Analysis of Acetyl-CoA and Histone Modification via Mass Spectrometry to Investigate Metabolically Driven Acetylation
Acetylation is a highly abundant and dynamic post-translational modification (PTM) on histone proteins which, when present on chromatin bound histones, facilitates the accessibility of DNA for gene transcription. The central metabolite, acetyl-CoA, is a substrate for acetyltransferases, which cataly...
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| 出版年: | Methods Mol Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462437/ https://ncbi.nlm.nih.gov/pubmed/30725455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9027-6_9 |
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