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Integrated Analysis of Acetyl-CoA and Histone Modification via Mass Spectrometry to Investigate Metabolically Driven Acetylation

Acetylation is a highly abundant and dynamic post-translational modification (PTM) on histone proteins which, when present on chromatin bound histones, facilitates the accessibility of DNA for gene transcription. The central metabolite, acetyl-CoA, is a substrate for acetyltransferases, which cataly...

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書目詳細資料
發表在:Methods Mol Biol
Main Authors: Sidoli, Simone, Trefely, Sophie, Garcia, Benjamin A., Carrer, Alessandro
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462437/
https://ncbi.nlm.nih.gov/pubmed/30725455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9027-6_9
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