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Characterization of individual histone post-translational modifications and their combinatorial patterns by mass spectrometry-based proteomics strategies

Histone post-translational modifications (PTMs) play an essential role in chromatin biology, as they model chromatin structure and recruit enzymes involved in gene regulation, DNA repair and chromosome condensation. Such PTMs are mostly localized on histone N-terminal tails where, as single units or...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods Mol Biol
Hauptverfasser: Sidoli, Simone, Garcia, Benjamin A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240223/
https://ncbi.nlm.nih.gov/pubmed/27854019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6630-1_8
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