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Characterization of individual histone post-translational modifications and their combinatorial patterns by mass spectrometry-based proteomics strategies
Histone post-translational modifications (PTMs) play an essential role in chromatin biology, as they model chromatin structure and recruit enzymes involved in gene regulation, DNA repair and chromosome condensation. Such PTMs are mostly localized on histone N-terminal tails where, as single units or...
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| Veröffentlicht in: | Methods Mol Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5240223/ https://ncbi.nlm.nih.gov/pubmed/27854019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6630-1_8 |
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