Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

BACKGROUND: Fludarabine is often used as an important drug in reduced toxicity conditioning regimens prior to hematopoietic cell transplantation (HCT). As no definitive pharmacokinetic (PK) basis for HCT dosing for the wide age and weight range in HCT is available, linear body surface area (BSA)-bas...

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Detalles Bibliográficos
Publicado en:Clin Pharmacokinet
Main Authors: Langenhorst, Jurgen B., Dorlo, Thomas P. C., van Maarseveen, Erik M., Nierkens, Stefan, Kuball, Jürgen, Boelens, Jaap Jan, van Kesteren, Charlotte, Huitema, Alwin D. R.
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2018
Assuntos:
Original Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451721/
https://ncbi.nlm.nih.gov/pubmed/30327943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0715-9
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