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Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

BACKGROUND: Fludarabine is often used as an important drug in reduced toxicity conditioning regimens prior to hematopoietic cell transplantation (HCT). As no definitive pharmacokinetic (PK) basis for HCT dosing for the wide age and weight range in HCT is available, linear body surface area (BSA)-bas...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Langenhorst, Jurgen B., Dorlo, Thomas P. C., van Maarseveen, Erik M., Nierkens, Stefan, Kuball, Jürgen, Boelens, Jaap Jan, van Kesteren, Charlotte, Huitema, Alwin D. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451721/
https://ncbi.nlm.nih.gov/pubmed/30327943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0715-9
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