Population Pharmacokinetics of Fludarabine in Children and Adults during Conditioning Prior to Allogeneic Hematopoietic Cell Transplantation

BACKGROUND: Fludarabine is often used as an important drug in reduced toxicity conditioning regimens prior to hematopoietic cell transplantation (HCT). As no definitive pharmacokinetic (PK) basis for HCT dosing for the wide age and weight range in HCT is available, linear body surface area (BSA)-bas...

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Bibliografske podrobnosti
izdano v:Clin Pharmacokinet
Main Authors: Langenhorst, Jurgen B., Dorlo, Thomas P. C., van Maarseveen, Erik M., Nierkens, Stefan, Kuball, Jürgen, Boelens, Jaap Jan, van Kesteren, Charlotte, Huitema, Alwin D. R.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Original Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451721/
https://ncbi.nlm.nih.gov/pubmed/30327943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-018-0715-9
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