Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

Optimal fludarabine exposure has been associated with improved treatment outcome in allogeneic hematopoietic cell transplantation, suggesting potential benefit of individualized dosing. A randomized controlled trial (RCT) comparing alternative fludarabine dosing strategies to current practice may be...

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Dades bibliogràfiques
Publicat a:CPT Pharmacometrics Syst Pharmacol
Autors principals: Langenhorst, Jurgen B., Dorlo, Thomas P.C., van Kesteren, Charlotte, van Maarseveen, Erik M., Nierkens, Stefan, de Witte, Moniek A., Boelens, Jaap Jan, Huitema, Alwin D.R.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239337/
https://ncbi.nlm.nih.gov/pubmed/31957334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12486
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