Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

Optimal fludarabine exposure has been associated with improved treatment outcome in allogeneic hematopoietic cell transplantation, suggesting potential benefit of individualized dosing. A randomized controlled trial (RCT) comparing alternative fludarabine dosing strategies to current practice may be...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Langenhorst, Jurgen B., Dorlo, Thomas P.C., van Kesteren, Charlotte, van Maarseveen, Erik M., Nierkens, Stefan, de Witte, Moniek A., Boelens, Jaap Jan, Huitema, Alwin D.R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239337/
https://ncbi.nlm.nih.gov/pubmed/31957334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12486
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