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Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase

Pif1 is a multifunctional helicase and DNA processing enzyme that has roles in genome stability. The enzyme is conserved in eukaryotes and also found in some prokaryotes. The functions of human PIF1 (hPIF1) are also critical for survival of certain tumour cell lines during replication stress, making...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Dehghani-Tafti, Saba, Levdikov, Vladimir, Antson, Alfred A, Bax, Ben, Sanders, Cyril M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6451128/
https://ncbi.nlm.nih.gov/pubmed/30698796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz028
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