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Papillomavirus E1 helicase assembly maintains an asymmetric state in the absence of DNA and nucleotide cofactors

Concerted, stochastic and sequential mechanisms of action have been proposed for different hexameric AAA+ molecular motors. Here we report the crystal structure of the E1 helicase from bovine papillomavirus, where asymmetric assembly is for the first time observed in the absence of nucleotide cofact...

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Hlavní autoři: Sanders, Cyril M., Kovalevskiy, Oleg V., Sizov, Dmytro, Lebedev, Andrey A., Isupov, Michail N., Antson, Alfred A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2095799/
https://ncbi.nlm.nih.gov/pubmed/17881379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm705
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