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Papillomavirus E1 helicase assembly maintains an asymmetric state in the absence of DNA and nucleotide cofactors
Concerted, stochastic and sequential mechanisms of action have been proposed for different hexameric AAA+ molecular motors. Here we report the crystal structure of the E1 helicase from bovine papillomavirus, where asymmetric assembly is for the first time observed in the absence of nucleotide cofact...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2095799/ https://ncbi.nlm.nih.gov/pubmed/17881379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm705 |
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